Heyman uses the phenomenon of addiction to make a profound point about neuroscientific progress in general. “The implication is that as we learn more about a disorder,” he writes, “the more likely it is to be thought of as a disease”—and, consequently, as a condition whose course cannot be modified by its foreseeable consequences. Indeed, reconciling advances in brain science with their meaning for personal, legal, and civic notions of agency and responsibility will be one of our next major cultural projects.